MMP7 and idiopathic pulmonary fibrosis: Finally, to demonstrate the robustness of these novel functional readouts, we correlated these data with a biomarker involved in the extra cellular matrix (ECM) remodeling, such as metalloproteinase-7 (MMP-7), one of the most promising prognostic biomarkers in IPF, for which it is reported a correlation with disease severity, as assessed by FVC and DFCO, in several clinical studies (Inoue et al., 2020).