The CD3+ (502.00 vs. 882.65 cells/mm3, P<0.001), CD3+CD4+ (324.48 vs. 670.45 cells/mm3, P<0.001), CD3+CD8+ (162.69 vs. 229.60 cells/mm3, P=0.048), and CD16+CD56+ (89.00 vs. 125.30 cells/mm3, P=0.002) cell counts in the CADM group were significantly lower than those in the CDM group. The gene discussed is CD4; the disease is clinically amyopathic dermatomyositis.