The rates of anti-MDA5 antibodies (P=0.030), ILD (P=0.025), RP-ILD (P=0.032), cough or dyspnea (P=0.009), and the levels of CRP (P=0.004) and neutrophils (P=0.023) in dead patients with CADM were significantly higher than those in dead patients with CDM. Here, IFIH1 is linked to interstitial lung disease.