M1, activated by toll‐like receptor (TLR), tumor necrosis factor (TNF)‐α, interferon‐gamma (IFN‐γ), and CSF2, has pro‐inflammatory, anti‐tumor, and bactericidal functions, with markers such as CD86, CD11c, HLA‐DR, iNOS, and pSTAT1.10 The gene discussed is TNF; the disease is neoplasm.