As for ACC, the prognosis was negatively related to ACBD3 expression, including OS (HR = 2.56, 95% CI: 1.17–5.61, p = 0.018), DSS (HR = 2.60, 95% CI: 1.15–5.88, p = 0.022), and PFI (HR = 4.02, 95% CI: 2.02–8.03, p < 0.001). The gene discussed is ACBD3; the disease is adrenal cortex carcinoma.