WNT11 and rheumatoid arthritis: We found for the first time that the expression of Wnt11 was significantly increased in RA synovium (Fig. 3A), RA FLS (Fig. 3B), CIA synovium (Fig. 3C), and CIA FLS (Fig. 3D), with its expression level about 2–3 times that of the normal group, indicating that Wnt11 was involved in RA pathology.