Simple regression revealed that Asprosin, NT-ProBNP, TC, TG, HDL-c, LDL-c, ApoA1, Apo B, BUN, Cr, FBG, HbA1C, LVEF, IVS, LVPW, LAD, LVEDD, gender, age, no CAD and no DM were the influential HF factors, with statistically significant differences. This evidence concerns the gene APOA1 and diabetes mellitus.