There were significant differences in TC, TG, HDL-C, LDL-C, ApoA1, ApoB, AST, Cr, BUN, FBG, HbA1C, NT-ProBNP, IVS, LVPW, LAD, LVEDD, E/e′, LVEF, prevalence of DM, prevalence of HBP, prevalence of CAD and prevalence of HF among the three groups. The gene discussed is APOB; the disease is hydrops fetalis.