In addition, ApoA1, Cr, NT-proBNP, the prevalence of HBP, CAD and HF, and LAD increased significantly with increasing serum Asprosin levels, while LVEF decreased with increasing Asprosin levels, and the differences were statistically significant (P < 0.05) (Table 2; Fig. 2). This evidence concerns the gene NPPB and hydrops fetalis.