Gupta et al. summarized the expression of 207 glycation genes in TCGA database and identified 6 glycation genes (B3GNT3, B4GALNT3, FUT3, FUT6, GCNT3 and MGAT3) that played a unique role in the pathogenesis of PC [33]. Here, B3GNT3 is linked to pachyonychia congenita.