The time-dependent ROC curve analysis of DPH2 expression suggested that the AUC values of both TCGA-LIHC (Fig. S7G) and ICGC-LIHC-JP (Fig. S7I) datasets for survival at 1, 2, and 3 years are greater than 0.65, indicating that the gene has good predictive ability for liver cancer prognosis, while the NODE-HCC dataset revealed that DPH2 lacks predictive ability (Fig. S7H). The gene discussed is DPH2; the disease is hepatocellular carcinoma.