The Eμ-MycT/+;Arrdc3−/− lymphomas were more immature in origin (>60% tumours were majority B220+/IgD-/IgM- pro-B/pre-B) compared to the Eμ-MycT/+;Arrdc+/+ lymphomas (>60% tumours were majority B220+/IgD-/IgM+ immature B) (Figure S8C). The gene discussed is CD40LG; the disease is neoplasm.