For instance, compared to Zeb1WT/ApoeKO mice, Zeb1∆M/ApoeKO mice had higher body weight, greater steatosis, higher WAT immune infiltration, higher serum levels of pro-inflammatory markers (IL1β, IL2, IL12, leptin, CCL2), higher cholesterol and LDL, and lower HDL and glucose tolerance. This evidence concerns the gene LEP and steatosis.