Since we found that Il1rl1 expression is restricted in ILC2s (Figs. 3e, 5e, and 6c), Ifngr1-/-Rag2-/-Il33gfp/gfp mice were generated to examine the importance of the IL-33-ILC2 axis in PF. This evidence concerns the gene IL1RL1 and pemphigus foliaceus.