The results showed that patients with high RNA level of EFNB1 (≥10.6 TPM) or EPHB4 (≥9.2 TPM) in ESCC had shorter survival time than those with low RNA level of EFNB1 (<10.6 TPM) or EPHB4 (<9.2 TPM) although the statistical significance were marginally (P = 0.04 and P = 0.05 for log-rank test; Fig. 4h). Here, EFNB1 is linked to esophageal squamous cell carcinoma.