However, patients with high score of both EFNB1 and EPBH4 levels (≥11.3 TPM) had significantly worse prognosis than those with low score of both EFNB1 and EPBH4 level (<11.3 TPM; log-rank P < 0.003) and the hazard ratio for death adjusted for sex, age, and tumor stage was 2.09 (95% CI = 1.12–3.92; Fig. 4h). The gene discussed is EFNB1; the disease is neoplasm.