These two cell types, typically defined by expression of Ly6g (neutrophils) and Adgre1 (F4/80, macrophages), expressed a similar transcriptional program following infection, including S100a8/9, Lcn2, Cxcl1, and Il1b (Fig. 6 and SI Appendix, Fig. S8). Here, ADGRE1 is linked to infection.