TPX2 and cancer: For example, PLK1 is categorized as an oncogene and is highly overexpressed in various cancer cells, including gastric, breast, and liver cancers (80–82); TPX2 is also overexpressed in cancers and is considered a diagnostic and prognostic marker for malignancies (83); and KIF20A has been observed to be upregulated in and capable of regulating malignant behavior in numerous cancer types (84–86).