Additionally, the ICBcomb database contains 111 human samples from 10 datasets treated with PD-1/PD-L1 inhibitors across six disease types: chronic lymphocytic leukemia (CLL), HCC, lymphoma, melanoma, uveal melanoma (UM) and colorectal carcinoma (CRC) (Table 1). Here, CD274 is linked to B-cell chronic lymphocytic leukemia.