AIP and neoplasm: In previous studies, we and other authors reported that the aryl hydrocarbon receptor interacting protein (AIP), which was identified in 2006 as a tumor suppressor gene in GH- and/or PRL-secreting PitNETs [14] and currently represents the main predisposing gene for the development of such tumors [15, 16], could be paradoxically overexpressed in NF/GnPT [17, 18].