For instance, the lncRNA PCA3 (Prostate Cancer Antigen 3) is used as a diagnostic marker for prostate cancer, and it can be easily found in urine samples (Taheri et al. 2022); the lncRNA HOTAIR (HOX antisense intergenic RNA) is involved in hormone therapies resistant in breast cancer (Xue et al. 2016). The gene discussed is PCA3; the disease is Familial prostate cancer.