RENBP and metabolic disease: Additionally, some disease-causing pathways were enriched, which could be divided into three parts: I) “Infectious/immune disease” (Human papillomavirus infection; Amoebiasis; Rheumatoid arthritis); II) “Cardiovascular disease” (Dilated cardiomyopathy; Hypertrophic cardiomyopathy); III) “Endocrine and metabolic disease” (AGE-RAGE signaling pathway in diabetic complications).