C1QA and Anxiety: For example, we identified downregulated C1QA expression, a gene with documented links with anxiety-like behavior (Bai et al., 2022; Maras et al., 2022), ostensibly through its role in inflammation, and Alzheimer’s disease, through its role in synapse elimination and neuronal damage (Hong et al., 2016; Dejanovic et al., 2018; Wu et al., 2019).