Furthermore, isovitexin (Sun et al., 2021), β-caryophyllene (Li et al., 2021b), cichoric acid (Wang et al., 2021b), resveratrol (Li et al., 2019b), carvacrol (Riaz et al., 2022) and bran saponins (Lin et al., 2023) can offer a safeguarding impact against gout by suppressing the NF-κB signaling pathway. Here, NFKB1 is linked to gout.