Of note, 4 genes were downregulated (fold change ≤ 0.5, p ≤ 0.05, genes indicated in green) following S. epidermidis peritonitis, coding notably for anti-atherosclerotic mediators, such as PPARG, a receptor whose activation leads to potent anti-atherosclerotic responses (Li and Glass, 2004; Li et al., 2004), IL-5, which slows down atherosclerosis progression (Binder et al., 2004), and ApoE, which mediates lipid clearance from plasma (Bouchareychas and Raffai, 2018). Here, APOE is linked to atherosclerosis.