TGFB1 and pulmonary fibrosis: TGFβ signaling plays a central role in promoting the transition of lipofibroblasts to myofibroblasts during the pathogenesis of lung fibrosis (El Agha et al., 2017; Saito et al., 2018; Ye and Hu, 2021), and activation of TGFβ signaling has also been linked with the development of several aging-associated disorders (Tominaga and Suzuki, 2019).