DVL2 and gastric cancer: revealed that circ_0091741 is highly expressed in GC cells and their secreted exosomes, and mechanistically, GC cell-derived exosomal circ_0091741 competitively binds miR-330-3p, decreasing its binding to the target gene TRIM14, thereby increasing TRIM14 expression, and TRIM14 overexpression promotes GC cell autophagy and oxaliplatin (OXA) resistance, Furthermore, TRIM14 can activate the Wnt/β-catenin signaling pathway by stabilizing Dvl2, thus exosomal circ_0091741 promotes GC cell autophagy and chemoresistance through the miR-330-3p/TRIM14/Dvl2/Wnt/β-catenin axis (89).