Univariate Cox regression analysis was conducted on numerous variables, including chronic kidney disease, heart rate, creatinine, uric acid, cystatin C, lipoprotein (a), homocysteine, AST, ALT, fibrinogen, D-dimer, LVEF, the SYNTAX score, MVD, calcified lesions, and CTO (P < 0.05). The gene discussed is GPT; the disease is chronic kidney disease.