GNAQ and uveal melanoma: However, the list of studiesperformed in vivo is rather short, despite their promising outcomes,and revolves around the investigation of asthma bronchiale, pain, thrombosis, and uveal melanoma.19,45,68 Importantly, Gαq proteinsin rat and mouse are identical to the human Gαq proteinwith the exception of one amino acid in the helical domain (I91 Vfrom human to mouse/rat).