Based on our investigation of the infiltration of various immune cells into the microenvironment of HCC, we found that the enrichment scores of B cells, CD8 T cells, DC, Cytotoxic cells, Eosinophils, Mast cells, Neutrophils, NK CD56bright cells, NK cells, pDC, Tcm, Th17 cells, and Th2 cells in the high MRPL48 expression group were significantly different than that in the low MRPL48 expression group (Fig. 7A). The gene discussed is CD8A; the disease is hepatocellular carcinoma.