KLK3 and metastasis: Multivariate analysis showed that PSA (OR: 1.075, P < 0.001), Gleason score (OR: 2.904, P < 0.001), DD (OR: 2.152, P < 0.001) and Fib (OR: 1.706, P = 0.007)were independent risk factors for bone metastasis of Pca after adjusting for Age, BMI and other confounding factors (Table 4).