MITF and neoplasm: We also demonstrated that docetaxel, a taxane agent in clinical use, increased miR-125b expression and promoter activity in adherent (Fig. 1B, Fig. S2A), spheroidal (Fig. S2B) and tumor xenograft (Fig. S2C) forms of the endogenously high miR-125b-expressing human breast cancer cell line MDA-MB-231miR-125bprom-EGFP, which harbors a lentiviral construct that expresses EGFP, driven by the hsa-miR-125b-1 promoter sequences (abbreviated Mi/EGFP; miR-125b expression is shown to correlate with Mi/EGFP level; Fig. S2D).