Besides, accumulating evidence demonstrates that DACH1 acts as a tumor suppressor in multiple types of cancers, including but not limited to breast cancer, non-small cell lung cancer [32, 33], gastric cancer [34], esophageal cancer [35], hepatocellular carcinoma [36, 37], renal carcinoma [38], and colorectal cancer [39]. Here, DACH1 is linked to breast cancer.