TP53 and cancer: It is crucial in promoting EMT in cancer, including CC [22]; its expression is inhibited by miR200, which is activated by suppressor gene TP53 [23]; ZEB1 is known to be involved in regulating key factors in malignant cells at the invasive front of carcinomas, conferring a proinvasive and stem-like phenotype on cancer cells, as well as leading to a worse clinical prognosis in several human cancers [24].