Previous studies from our research group have shown that dysbiosis associated with non-alcoholic fatty liver disease (NAFLD) [currently termed as metabolic dysfunction-associated steatotic liver disease (MASLD)] like conditions following MC-LR exposure results from the activation of nucleotide-binding domain-like receptor protein 3 (NLRP3) inflammasome [21, 22]. The gene discussed is NLRP3; the disease is metabolic dysfunction-associated steatotic liver disease.