Data showed that those who declined frailty assessments were significantly more likely to have peripheral vascular disease (PVD) (61.5% vs. 13.3%, p = 0.001), low albumin (3.4 g/dL vs. 3.8 g/dL, p = 0.0187), low sodium (128.4 mmol/L vs. 136.8 mmol/L, p = 0.0422), use of vasodilator medications (53.8% vs. 20.0%, p = 0.031) and been declined for kidney transplant listing (100% vs. 53.5%, p = 0.005). This evidence concerns the gene ALB and peripheral vascular disease.