The related pathways involved include Lipid and atherosclerosis signalling pathway, PI3K-Akt signalling pathway, Kaposi sarcoma-associated herpesvirus infection signalling pathway, antiviral infection (hepatitis B) signalling pathway, Human cytomegalovirus infection signalling pathway, AGE-RAGE signalling pathway, Cancer pathway. The gene discussed is AKT1; the disease is atherosclerosis.