MPPE1 and influenza: In corroboration of these influenza-related findings, lung DC in hyperglycaemic mice infected with PVM evidenced a depletion in lung cDC1, cDC2 and pDC (Fig. 2d and Extended Data Fig. 5m,n), coupled with fewer Ki-67+ DC and lower IL-12 expression in lung cDC1 (Extended Data Fig. 5o,p), compared with PVM-infected, normoglycaemic mice.