In addition, in univariate Cox proportional model analysis, a lower Mg × K product, old age, lower prealbumin level, hypoalbuminemia, and high hs-CRP were significant factors associated with increased mortality risk, whereas in multivariate Cox proportional analysis adjusted for potential confounding factors, low Mg × K was still an independent risk factor for mortality (Table 3, models 1 and 2), but it lost power of predictor for mortality after including serum albumin and hs-CRP into analysis (model 3). The gene discussed is TTR; the disease is Hypoalbuminemia.