When we evaluated the expression of the main RAS markers in the liver samples, we observed that there was an increase in the expression of Agt and At1, both in 129sve T1D mice (p = 0.0040) and in 129sve T1D mice treated with Cap (p = 0.0019) for Agt, and in 129sve T1D mice treated with Cap (p = 0236) for At1 and that, differently from what was observed in the muscle, appears to be dependent on the presence of LTs, since there is no differences at gene levels for these markers in the groups from 129 5LO−/− mice (Fig. 5A–D). The gene discussed is AGT; the disease is type 1 diabetes mellitus.