For Sample #A4 (Fig. 4A and B), areas predicted as ICCA-like were indeed associated with increased expression of genes related to cholangiocyte differentiation (e.g EPCAM, HNF1B and KRT7) and decreased expression of well-known hepatocytic markers (ALB, FABP1 and APOB) (Fig. 4B and Supplementary Data 1). This evidence concerns the gene ALB and infantile convulsions and choreoathetosis.