Top enriched GO terms common to both dynamic and static male-biased DHS included lipid metabolic process and steroid metabolic process, consistent with the major role that GH plays in the male-prevalence of fatty liver development and liver metabolic disease (Dichtel et al., 2022; Kaltenecker et al., 2019; Oxley et al., 2023). The gene discussed is GH1; the disease is fatty liver disease.