treatment of cancer cells (HepG2, HT29, MCF) with lactoferrin–oleic acid complexes (LF–OA) inducedthe activation of mitochondria apoptosis pathway, which correspondedwith expression of caspase-3 and pro-apoptic Bax protein; overexpression of p-JKN regulator confirmed the possibility of death receptor-mediated apoptosis pathway. The gene discussed is BAX; the disease is cancer.