In addition, another 6 genes, PRKDC, NCL, CCNA2, AXL, GLI3, and SUPT5H, were identified to be highly related to the growth and development of breast cancer; the overall and postprogression survival in patients with breast cancer; the regulation of the gene expression that controls the proliferation, migration, cell cycle, and apoptosis of breast cancer MDA-MB-231 cells; and so on. The gene discussed is NUCLEOLIN; the disease is breast cancer.