Moreover, the same research group identified three single-nucleotide polymorphisms (SNPs) from NHE3 (missense variant: C2405T; promoter variants: G1131A and C1197T) that were significantly associated with SIDS [7] and might explain the previously reported overexpression of NHE3 in the brainstem. The gene discussed is SLC9A3; the disease is sudden infant death syndrome.