Interestingly, after a meta-analysis using all three datasets, genotype AA of SNP rs2247114 (C2405T) was highly associated with SIDS (p = 0.0008, SIDS: 6.4%, controls: 2.1%), suggesting that NHE3 might indeed be involved in the etiology of SIDS. This evidence concerns the gene SLC9A3 and sudden infant death syndrome.