In our future studies, we will further investigate and refine the specific mechanisms of abnormal regulation of YAP/TAZ in tumors, and focus on the specific mechanisms of polarization of TAMs by key factors at all levels of the Hippo pathway, so as to optimize the mechanisms of immune regulation, dig deep into the molecular mechanisms and biological properties of tumor-associated macrophages, better understand their functions and regulatory mechanisms and provide references for the development of more effective therapeutic approaches. Here, YAP1 is linked to neoplasm.