The most common AEs of the triple combination modality were fever, abdominal pain, and liver function damage related to TACE (12, 13); hypertension, diarrhea, and HFSR related to TKIs (7, 13) and rash, fatigue, and pruritus related to PD-1 inhibitors (3, 24, 25). Here, PDCD1 is linked to hypertensive disorder.