ALOX5 and nonpapillary renal cell carcinoma: At the mRNA level, significantly increased ALOX5 and TRIB3 expression was evident in ccRCC samples, whereas the opposite was evident for DPEP1, HADH, PLIN2, SCD5, SLC44A4, and UGT8, with differential expression being most significant for ALOX5 (Figure 10A).