TNF and allergic disease: IL-17A can induce allergen-specific Th2 cell activation and eosinophil and neutrophil accumulation (16), has synergistic effects with other cytokines, such as TNF-α, IFN-γ, andIL-1, and plays a key role in barrier immunity and allergic diseases (17, 19).A study conducted by Magdalena Żbikowska-Gotz found that during the period of obvious clinical symptoms in FA patients, the levels of IL-17A in their blood were significantly higher than those in healthy controls (33).