Our GBA1 mutation carriers with FOG demonstrated more severe motor disability and more frequent motor complications in PD, aligning with our previous observational study (Ou et al., 2014) as well as several studies conducted on Caucasian populations (Giladi et al., 1992; Lamberti et al., 1997; Giladi et al., 2001). This evidence concerns the gene GBA1 and Parkinson disease.