CD4 and IgA glomerulonephritis: An increase in the number of CD4(+) epipharyngeal abrasive cells has also been reported by Hotta et al. [5], who demonstrated that the number of CD4(+) T cells, especially CD4(+) HLA-DR(+) cells representing activated helper T cells, in the epipharyngeal abrasive cells was significantly increased in patients with IgA nephropathy, which is one of the EAT-effective diseases.