PIN1 and cancer: Peptidylprolyl cis-trans isomerase NIMA-interacting 1 (Pin1) is a regulator that specifically interacts with phosphorylated Ser/Thr-Pro (pS/T-P) motifs and catalyzes cis/trans isomerization, leading to conformational changes of its substrates that are involved in cancer development (Lu et al., 1996; Yaffe et al., 1997; Lu et al., 2002; Lu and Zhou, 2007).