MGMT and central nervous system cancer: Genetic factors also occupied an essential role, and many molecular diagnostic markers in glioma have been discovered, such as IDH, codeletion of chromosomal arms 1p and 19q (1p/19q codeletion), H3F3A, nuclear alpha‐thalassemia/mental retardation X‐linked syndrome (ATRX) gene, O6‐methylguanine‐DNA methyltransferase (MGMT), and telomerase reverse transcriptase (TERT) [19].