In addition to regulating cholesterol transport, genes involved in lipid metabolism, including lipogenic targets SREBP1, fatty acid synthase (FASN) [37], low‐density lipoprotein receptor (LDLR) [38], and apolipoprotein E (APOE), are also suggested to contribute to LXR‐mediated antiproliferation and proapoptosis in different cancer types. This evidence concerns the gene SREBF1 and cancer.